Bộ sách luyện thi ETS 2023 LC&RC
199,000₫
299,000₫
Sách Neurotoxicity of Aluminum, 2nd Edition (sách keo gáy, bìa mềm)
Categories:Reference - Other Reference By Subject
Year:2023
Edition:2nd
Language:english
Pages:324
This book reviews the scientific literature and the authors’ own
research linking aluminum neurotoxicity with cognitive impairment and
Alzheimer’s disease (AD). It focuses on aluminum levels in the brain,
region-specific and subcellular distribution, its relation to
neurofibrillary tangles and amyloid beta—the pathological features of
AD, and the possible mechanism of aluminum inducing these pathological
features. Further, the book stresses the importance of aluminum’s
complex speciation chemistry in relation to biology, and details
aluminum’s mechanism in oxidative stress and cell death, especially in
connection with apoptosis and necroptosis. The electrophysiological
variation and synaptic plasticity induced by aluminum are covered, while
the metal’s debatable role in AD and the cross-talk between aluminum
and genetic susceptibility are also discussed, and more recently the
relationship between aluminum-induced epigenetic modification on DNA and
non-coding RNAs and neuron death and synaptic impairment. The second
edition updates eight chapters according to the most recent researches.
Content about aluminum-induced AD-like pathological features, neurotoxic
effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina
nanoparticles induced neurotoxic and neurodevelopmental toxic effects is
also added. In closing, this book provides readers with a systematic
summary of aluminum neurotoxicity.
